NAD+
Essential redox coenzyme central to energy metabolism and cellular-aging research.
Nicotinamide adenine dinucleotide (NAD+) is a coenzyme present in every living cell, where it shuttles electrons between reactions as part of central energy metabolism. Cellular NAD+ availability declines with age, which has made it a focal point of metabolic and longevity research.
Beyond its redox role, NAD+ is consumed as a substrate by sirtuins and PARP enzymes involved in gene regulation and DNA repair. Studies of NAD+ and its precursors examine mitochondrial function, sirtuin signaling, and age-related metabolic decline in cell and animal models.
Available in the catalog
NAD+ from $42.49
Specifications
- Molecular formula
- C₂₁H₂₇N₇O₁₄P₂
- Molecular weight
- 663.43 g/mol
- CAS number
- 53-84-9
- Synonyms
- β-NAD, Nicotinamide adenine dinucleotide
Research areas
Stability information
Lyophilized (powder)
−20°C · up to 2 years
Reconstituted
2–8°C · up to 14 days
Peer-reviewed research
Independent, published literature on this compound. Links open a PubMed search.
Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence
Rajman L, Chwalek K, Sinclair DA
View source Science · 2015NAD+ in aging, metabolism, and neurodegeneration
Verdin E
View source The EMBO Journal · 2017Modulating NAD+ metabolism, from bench to bedside
Katsyuba E, Auwerx J
View sourceImportant research notice
This content is provided for laboratory and educational purposes only. All compounds are sold strictly for in-vitro research and are not intended to diagnose, treat, cure, or prevent any disease, and are not for human or veterinary use.